Carbamic acid, [2-(3-azetidinyl)ethyl]-, 1,1-dimethylethyl ester (9CI) - Names and Identifiers
Name | 3-(N-Boc-aminoethyl)azetidine
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Synonyms | 3-Boc-aminoethylazetidine 3-(N-Boc-aminoethyl)azetidine 2-(azetin-3-yl)-1-(n-boc)ethylaMine tert-butyl (1-azetidin-3-ylethyl)carbamate tert-butyl N-[2-(azetidin-3-yl)ethyl]carbamate 2-(Azetin-3-yl)-1-(N-BOC)ethylamine hydrochloride tert-butyl 3-(2-aminoethyl)azetidine-1-carboxylate CarbaMic acid, [2-(3-azetidinyl)ethyl]-, 1,1-diMethylethyl ester Carbamic acid, [2-(3-azetidinyl)ethyl]-, 1,1-dimethylethyl ester (9CI)
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CAS | 162696-31-3
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InChI | InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-6-8(7-12)4-5-11/h8H,4-7,11H2,1-3H3 |
Carbamic acid, [2-(3-azetidinyl)ethyl]-, 1,1-dimethylethyl ester (9CI) - Physico-chemical Properties
Molecular Formula | C10H20N2O2
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Molar Mass | 200.28 |
Density | 1.004 |
Melting Point | 84-86℃ |
Boling Point | 302℃ |
Flash Point | 136℃ |
Vapor Presure | 0.00429mmHg at 25°C |
Appearance | Powder |
Color | White to pale brown |
pKa | 12.81±0.46(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.49 |
Carbamic acid, [2-(3-azetidinyl)ethyl]-, 1,1-dimethylethyl ester (9CI) - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
Carbamic acid, [2-(3-azetidinyl)ethyl]-, 1,1-dimethylethyl ester (9CI) - Introduction
3-(N-Boc-aminoethyl)azetidine is an organic compound whose chemical name is N-tert-butoxycarbonyl-3-aminopropylaziridine. Here is some information about it:
Properties: 3-(N-Boc-aminoethyl)azetidine is a colorless to pale yellow liquid with a lower boiling point and melting point. It is soluble in organic solvents such as alcohols and ethers, but insoluble in water. It is stable in air, but decomposes easily at high temperatures or in the presence of strong oxidants.
Purpose: 3-(N-Boc-aminoethyl)azetidine is commonly used as a reagent and intermediate in organic synthesis. It can be used to synthesize other organic compounds, such as amino acid protecting groups, pharmaceutical intermediates, functional polymers, etc.
Preparation method: A common preparation method is to react aminoethyl azetidine with tert-butyl alcohol acid chloride to form 3-(N-Boc-aminoethyl)azetidine. The reaction is typically carried out under an inert atmosphere to avoid unwanted side reactions.
Safety Information: 3-(N-Boc-aminoethyl) The use of azetidine should follow the relevant safety procedures. It should be kept away from fire and high temperature and stored in a sealed container. Wear appropriate personal protective equipment such as chemical protective goggles and gloves during use. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary.
Last Update:2024-04-09 15:17:53